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LY 341495, Tocris Bioscience™

Product Code. 30001348
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Quantity:
1 mg
10 mg
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This item is not returnable. View return policy

Description

Highly potent and selective group II mGlu antagonist

Highly potent and selective group II metabotropic glutamate receptor antagonist (Ki/IC50 values are 2.3, 1.3, 173, 990, 6800, 8200 and 22000 nM for human mGlu2, mGlu3, mGlu8, mGlu7a, mGlu1a, mGlu5a and mGlu4a receptors respectively). Readily brain penetrant and active in vivo.

Disodium salt (Cat. No. 4062) also available.

Chemical Identifiers

CAS 201943-63-7
Molecular Formula C20H19NO5
Molecular Weight (g/mol) 353.374
InChI Key VLZBRVJVCCNPRJ-KPHUOKFYSA-N
Synonym 2s-2-amino-2-1s,2s-2-carboxycycloprop-1-yl-3-xanth-9-yl propanoic acid, 2-1s,2s-2-carboxycyclopropyl-3-9h-xanthen-9-yl-d-alanine, 1s,2s-2-s-1-amino-1-carboxy-2-9h-xanthen-9-yl ethyl cyclopropanecarboxylic acid, 1s,2s-2-1s-1-amino-1-carboxy-2-9h-xanthen-9-yl ethyl cyclopropane-1-carboxylic acid, 1s,2s-2-s-1-amino-1-carboxy-2-9h-xanthen-9-yl ethyl cyclopropane-1-carboxylic acid, 1s,2s-2-1s-1-amino-1-carboxy-2-9h-xanthen-9-yl ethyl cyclopropanecarboxylic acid, 1s,2s-2-s-1-amino-1-carboxy-2-9h-xanthen-9-yl-ethyl-cyclopropanecarboxylic acid, 1s,2s-2-1-amino-1-carboxy-2-9h-xanthen-9-yl-ethyl-cyclopropanecarboxylic acid, s-2-s-1-amino-1-carboxy-2-9h-xanthen-9-yl-ethyl-cyclopropanecarboxylic acid, 2 s-amino-2-2 s-carboxy-1 s-cyclopropyl-3-9h-xanthen-9-yl propionic acid
PubChem CID 9819927
IUPAC Name (1S,2S)-2-[(1S)-1-amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl]cyclopropane-1-carboxylic acid
SMILES C1C(C1C(CC2C3=CC=CC=C3OC4=CC=CC=C24)(C(=O)O)N)C(=O)O

Specifications

Quantity 1 mg
Formula Weight 353.37
Percent Purity >98%
Chemical Name or Material LY 341495
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