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LY 294002 hydrochloride, Tocris Bioscience™

Product Code. 30001204
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Quantity:
5 mg
25 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Prototypical PI 3-kinase inhibitor; also inhibits other kinases

LY 294002 hydrochloride is a prototypical PI 3-kinase inhibitor (IC50 values are 0.31, 0.73, 1.06 and 6.60 μM for PI 3-Kβ, PI 3-Kα, PI 3-Kδ and PI 3-Kγ respectively). Also inhibits other kinases including, CK2, mTOR, PLK1, PIM1 and PIM3. Inhibits proliferation and induces apoptosis in human colon cancer cells in vitro and in vivo. Suppresses proliferation of mESCs. Inhibits autophagic sequestration in rat hepatocytes.

Negative Control also available.

Chemical Identifiers

CAS 934389-88-5
Molecular Formula C19H18ClNO3
Molecular Weight (g/mol) 343.807
InChI Key OQZQSRICUOWBLW-UHFFFAOYSA-N
Synonym ly-294,002 hydrochloride, ly-294002 hydrochloride, ly 294002 hydrochloride, 2-4-morpholinyl-8-phenyl-4h-1-benzopyran-4-one hydrochloride, 2-morpholin-4-yl-8-phenylchromen-4-one hydrochloride, 2-morpholin-4-yl-8-phenyl-chromen-4-one, 2-morpholin-4-yl-8-phenylchromen-4-one,hydrochloride, 2-morpholino-8-phenyl-4h-chromen-4-one hydrochloride, 2-4-morpholinyl-8-phenyl-1 4h-benzopyran-4-one hydrochloride
PubChem CID 11957589
IUPAC Name 2-morpholin-4-yl-8-phenylchromen-4-one;hydrochloride
SMILES C1COCCN1C2=CC(=O)C3=C(O2)C(=CC=C3)C4=CC=CC=C4.Cl

Specifications

Quantity 5 mg
Formula Weight 343.81
Percent Purity >99%
Chemical Name or Material LY 294002 hydrochloride
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