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LRP5 Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 24899-1-AP-20UL
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Description
LDL related proteins, LRP 5 and LRP 6, are members of the LDL receptor superfamily, which were found to be involved in the canonical Wnt signaling pathway. Mammalian LRP 6 was shown to bind to Wnt 1 and enhance Wnt-induced developmental processes in Xenopus embryos. Mice lacking LRP 6 exhibited developmental defects that are similar to those caused by deficiencies in various Wnt proteins. Recent work also shows that Wnt proteins induce the binding of LRP 5 to Axin, leading Axin degradation and beta catenin stabilization.Specifications
| LRP5 | |
| Polyclonal | |
| Unconjugated | |
| LRP5 | |
| BMND1, EVR1, EVR4, HBM, LR3, LRP 5, LRP5, LRP7, OPPG, OPS, OPTA1, VBCH2 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 4041 | |
| -20°C | |
| Liquid |
| Immunofluorescence, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot | |
| 0.21 mg/mL | |
| PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
| O75197 | |
| LRP5 | |
| LRP5 Fusion Protein Ag19034 | |
| 20 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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