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Lovastatin, 97%, Thermo Scientific™ Product Code.: 15489537
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Lovastatin, 97%, Thermo Scientific™

Product Code. 15489537
5g
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5g
25g
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Product Code. 15489537

Brand: Thermo Scientific Alfa Aesar H52792.06

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Description

This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

Applications
Lovastatin is a cholesterol lowering drug and competitive inhibitor of HMG-CoA reductase, a rate limiting enzyme in cholesterol synthesis. Blocks the production of mevalonate, a critical compound in the production of cholesterol and isoprenoids. It increases cellular resistance to anticancer agents such as doxorubicin and induces apoptosis in myeloma cells. It causes cell cycle arrest in G1 and G2/M phases.

Solubility
Soluble in DMSO (10 mg/ml), ethanol (10 mg/ml), methanol, chloroform, acetone, acetonitrile, DMF, and water (0.4 µg/ml).

Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents and heat.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 75330-75-5
Molecular Formula C24H36O5
Molecular Weight (g/mol) 404.55
MDL Number MFCD00072164
InChI Key PCZOHLXUXFIOCF-BXMDZJJMSA-N
Synonym lovastatin, mevinolin, mevacor, monacolin k, lovalip, altoprev, lovalord, mevinacor, nergadan, 6alpha-methylcompactin
PubChem CID 53232
ChEBI CHEBI:40303
IUPAC Name (1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-methylbutanoateShow MoreShow Less
SMILES CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12

Specifications

Quantity 5g
Solubility Information Soluble in DMSO (10mg/ml),ethanol (10mg/ml),methanol,chloroform,acetone,acetonitrile,DMF,and water (0.4 μg/ml).
Formula Weight 404.56
Percent Purity 97%
Chemical Name or Material Lovastatin

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5 results found
Lot Number Certificate Type Date Catalog Number
Lot NumberZ27I020 Certificate TypeCertificate of Analysis Date01/02/2023 Catalog NumberH52792.06,H52792.14
Lot NumberZ30B049 Certificate TypeCertificate of Analysis Date07/12/2021 Catalog NumberH52792.06,H52792.14
Lot NumberM30E026 Certificate TypeCertificate of Analysis Date07/12/2021 Catalog NumberH52792.06,H52792.14
Lot NumberZ04F052 Certificate TypeCertificate of Analysis Date07/12/2021 Catalog NumberH52792.06,H52792.14
Lot NumberZ28C010 Certificate TypeCertificate of Analysis Date07/12/2021 Catalog NumberH52792.06,H52792.14

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