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Macherey-Nagel™ LIPODEX™ G Capillary Columns for GC
Enables many compounds to be analyzed without derivatization. Macherey-Nagel™ LIPODEX™ G Capillary Columns for GC are phases with eight γ-cyclodextrin glucose units for enantiomer separation in gas chromatography. This lipophilic phase with long nonpolar ligants is a chemically non-bonded phase.
Brand: Macherey-Nagel™ 723379.50
Alert:
Water as solvent is strictly forbidden for all cyclodextrin phases. It is recommended to dry the sample and dissolve it in an appropriate nonpolar solvent.
Description
A major advantage of LIPODEX columns are that many compounds can be analyzed without derivatization. However, for certain substances, enantioselectivity can be favorably influenced by formation of derivatives. Regioselective alkylation and/or acylation of the hydroxyl groups leads to lipophilic phases with varying enantioselectivity, which are well suited for GC enantiomer analyses.
It is not possible to make a general prediction about which LIPODEX™ phase could solve a given separation task. Even for compounds with small structural differences or within homologous series, the enantiodifferentiation can be quite different.
- Base material: cyclic oligosaccharides consisting of eight γ-cyclodextrin glucose units bonded through α-1,4-linkages
- octakis-(2,3-di-O-pentyl-6-O-methyl)-γ-cyclodextrin
- Ligands: R2=R3=pentyl, R6=methyl; n=3
- Recommended for menthol isomers, ketones, alcohols, carboxylic acid esters, terpenes
Specifications
For isothermal operations: 220°C, For short isotherms in a temperature program: 240°C | |
GC Capillary Column | |
Lipodex™ G | |
50 m | |
Non polar |
0.4 mm | |
0.25 mm | |
Enantiomer Separation | |
Lipodex™ G | |
1 Each |
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