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Tocris Bioscience™ KG 5

PDGFRβ, B-Raf, c-Raf, FLT3 and KIT inhibitor

1815.00 NOK - 6990.00 NOK

Specifications

Chemical Name or Material 2-(Methylthio)-6-[4-[5-[[3-(trifluoromethyl)phenyl]amino]-1H-1,2,4-triazol-3-yl]phenoxy]-4-pyrimidinamine
CAS 877874-85-6
Target Raf Kinase Inhibitors
Molecular Formula C20H16F3N7OS
Formula Weight 459.45
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
18780518
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Tocris Bioscience™
5260/10
10 mg
1815.00 NOK
10mg
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18780789
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Tocris Bioscience™
5260/50
50 mg
6990.00 NOK
50mg
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Description

Description

PDGFRβ and B-Raf allosteric inhibitor. Also inhibits c-Raf, FLT3 and KIT. Disrupts blood vessel formation in zebrafish embryos and inhibits angiogenesis in a mouse angiogenesis model. Inhibits growth of renal and pancreatic tumors in mice. Also arrests cells in prometaphase. Orally available.
Specifications

Specifications

2-(Methylthio)-6-[4-[5-[[3-(trifluoromethyl)phenyl]amino]-1H-1,2,4-triazol-3-yl]phenoxy]-4-pyrimidinamine
Raf Kinase Inhibitors
459.45
877874-85-6
C20H16F3N7OS
>98%
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Safety and Handling

Safety and Handling

Recommended Storage : Store at -20°C

SDS
Documents

Documents

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