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JNJ-10229570, MedChemExpress

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Description
JNJ-10229570 is an antagonist of melanocortin receptor 1 (MC1R) and melanocortin receptor 5 (MC5R), which inhibits sebaceous gland differentiation and the production of sebum-specific lipids. JNJ-10229570 inhibits the binding of 125I-NDP-α-MSH to cells expressing human MC1R and MC5R, with IC50 values of 270 nM and 200 nM, respectively.
Specifications
Specifications
Chemical Name or Material | JNJ-10229570 |
CAS | 524923-88-4 |
Color | Light Yellow |
Purity Grade Notes | Research |
Molecular Formula | C22H19N3O2S |
Quantity | 50 mg |
Solubility Information | DMSO : 62.5 mg/mL (160.47 mM; Need ultrasonic) |
SMILES | COC1=C(C=CC=C1)C(N(C2=C(C=CC=C2)OC)S/3)=NC3=N\C4=CC=CC=C4 |
Molecular Weight (g/mol) | 389.47 |
Formula Weight | 389.47 |
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Research purposes only
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JNJ-10229570, MedChemExpress
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