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  7. (±)-J 113397, Tocris Bioscience™

(±)-J 113397, Tocris Bioscience™

Product Code. 30001416
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Quantity:
10 mg
50 mg
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This item is not returnable. View return policy

Description

Potent and selective NOP antagonist

Potent and selective NOP receptor antagonist (IC50 values are 2.3, 1400, 2200 and > 10000 nM for NOP, κ, μ and δ-opioid receptors respectively). Inhibits nociceptin/orphanin FQ-induced hyperalgesia in the mouse tail-flick test.

Chemical Identifiers

CAS 217461-40-0
Molecular Formula C24H37N3O2
Molecular Weight (g/mol) 399.579
InChI Key MBGVUMXBUGIIBQ-UHFFFAOYSA-N
Synonym (±)-1-[(3R™, 4R™)-1-(Cyclooctylmethyl)-3-(hydroxymethyl)-4-piperidinyl]-3-ethyl-1, 3-dihydro-2H-benzimidazol-2-one
PubChem CID 21186500
IUPAC Name 1-[1-(cyclooctylmethyl)-3-(hydroxymethyl)piperidin-4-yl]-3-ethylbenzimidazol-2-one
SMILES CCN1C2=CC=CC=C2N(C1=O)C3CCN(CC3CO)CC4CCCCCCC4

Specifications

Quantity 50 mg
Formula Weight 399.57
Percent Purity >98%
Chemical Name or Material (±)-J 113397
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