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Tocris Bioscience™ ICG 001
Inhibits TCF/β-catenin-mediated transcription
Brand: Tocris Bioscience™ 4505/50
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Description
ICG 001 is an inhibitor of TCF/β-catenin-mediated transcription. Selectively inhibits β-catenin/CBP interaction; displays no effect on β-catenin/p300 interaction. Exhibits growth inhibitory effects in colon carcinoma cell lines (SW480 and HCT-116 cells); also displays efficacy in Min mouse and nude mouse SW620 xenograft models.
Specifications
(6S,9aS)-Hexahydro-6-[(4-hydroxyphenyl)methyl]-8-(1-naphthalenylmethyl)-4,7-dioxo-N-(phenylmethyl)-2H-pyrazino[1,2-a]pyrimidine-1(6H)-carboxamide | |
50 mg | |
C33H32N4O4 |
780757-88-2 | |
beta-Catenin Inhibitors | |
0.98 |
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Product Title
Tocris Bioscience™ ICG 001 > 50 mg
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