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Gibco™ Human SCF Recombinant Protein, PeproTech®

Recombinant Protein

836.00 NOK - 25000.00 NOK

Specifications

Accession Number P21583
For Use With (Application) ELISA, Functional Assay, Western Blot
Formulation protein with no preservative
Gene ID (Entrez) 4254
Molecular Weight (g/mol) 18.4 kDa
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Products 7
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
17840423
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Gibco™
300-07-100UG
100 ÎĽg
5410.00 NOK
100µg
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17810333
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Gibco™
300-07-10UG
10 ÎĽg
2035.00 NOK
10µg
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17830423
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Gibco™
300-07-1MG
1 mg
25000.00 NOK
1mg
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17861393
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Gibco™
300-07-250UG
250 ÎĽg
8770.00 NOK
250µg
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17841593
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Gibco™
300-07-2UG
2 ÎĽg
836.00 NOK
2µg
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17830823
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Gibco™
300-07-500UG
500 ÎĽg
15060.00 NOK
500µg
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17830993
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Gibco™
300-07-50UG
50 ÎĽg
3205.00 NOK
50µg
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Description

Description

Recombinant Human SCF is an 18.4 kDa polypeptide containing 165 amino acid residues, which corresponds to the sequence of the secreted soluble form of SCF. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

Stem cell factor (SCF) is the ligand of the c-Kit oncogene and is expressed by various structural and inflammatory cells in the airways. Binding of SCF by the c-Kit receptor leads to homodimerization of the receptor and the activation of signalling pathways such as PI-3, PLC-gamma, Jak/STAT, and MAP kinase pathways. SCF expression leads to the induction of mast cell survival and the expression and release of histamine, pro-inflammatory cytokines and chemokines. The inhibition of the SCF/c-Kit pathway leads to a decrease in histamine levels, mast cell and eosinophil infiltration, IL-4 production and airway hyperresponsiveness, suggesting this pathway may be a useful therapeutic target in inflammatory diseases such as asthma. At least two isoforms of SCF are known to exist.
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