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Gibco™ Human NT-3 Recombinant Protein, PeproTech®
Recombinant Protein
Brand: Gibco™ 450-03-10UG
1314.73 NOK valid until 2025-03-29
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Description
Recombinant Human NT-3 is a noncovalently linked homodimer of two 13.6 kDa polypeptide monomers (240 total amino acid residues). This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
The protein encoded by this gene is a member of the neurotrophin family, that controls survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NTF3-deficient mice generated by gene targeting display severe movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse.
Specifications
P20783 | |
protein with no preservative | |
27.2 kDa | |
10 μg | |
RUO | |
AI316846; AI835689; HDNF; Nerve growth factor 2; neurotrophic factor; neurotrophin 3; neurotrophin-3; neurotrophin-3 (HDNF/NT-3); NGF2; NGF-2; NT3; NT-3; NTF3; Ntf-3 | |
Ntf3 | |
Unconjugated | |
MYAEHKSHRG EYSVCDSESL WVTDKSSAID IRGHQVTVLG EIKTGNSPVK QYFYETRCKE ARPVKNGCRG IDDKHWNSQC KTSQTYVRAL TSENNKLVGW RWIRIDTSCV CALSRKIGRT | |
E. coli | |
≥ 98% by SDS-PAGE gel and HPLC analyses. |
ELISA, Functional Assay, Western Blot | |
4908 | |
Human NT-3 | |
E. coli | |
<1 EU/ μg | |
NTF3 | |
Determined by its ability to bind recombinant human TrkB Fc Chimera in a functional ELISA. | |
Recombinant | |
-20°C | |
Lyophilized |
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