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Tocris Bioscience™ GSK 343
Potent and selective SAM-competitive EZH2 inhibitor
Brand: Tocris Bioscience™ 6128/10
2044.01 NOK valid until 2024-12-16
Use promo code "21630" to get your promotional price.
This item is not returnable.
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Description
GSK 343 is a potent and selective SAM-competitive EZH2 inhibitor (IC50 = 4 nM), that exhibits >60 fold selectivity for EZH2 over EZH1 and a range of other methyltransferases. GSK 343 decreases H3K27me3 levels in breast cancer cells and inhibits proliferation of prostate cancer cell lines in vitro.Specifications
| N-[(1,2-Dihydro-6-methyl-2-oxo-4-propyl-3-pyridinyl)methyl]-1-(1-methylethyl)-6-[2-(4-methyl-1-piperazinyl)-4-pyridinyl]-1H-indazole-4-carboxamide | |
| >98% | |
| C31H39N7O2 |
| 1346704-33-3 | |
| 10 mg | |
| Observed MW: 541.69 |