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Description
Deoxycytidine analog that inhibits DNA synthesis. Metabolized to form gemcitabine triphosphate (dFdCTP) and gemcitabine diphosphate (dFdCDP). dFdCTD inhibits ribonucleotide reductase causing a reduction in cellular nucleotides. dFdCTP is incorporated in DNA resulting in DNA strand termination. Displays antitumor activity in vitro and in vivo.

Specifications
Specifications
Quantity | 50 mg |
Formula Weight | 299.66 |
Percent Purity | >99% |
Chemical Name or Material | Gemcitabine hydrochloride |
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Gemcitabine hydrochloride, Tocris Bioscience™ >
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