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Tocris Bioscience™ FTY 720
Potent S1P receptor agonist; also immunosuppressant
1525.00 NOK - 5660.00 NOK
Specifications
Product Type | Agonist |
---|---|
Target Proteins | Sphingosine-1-phosphate Receptor |
CAS | 162359-56-0 |
Molecular Formula | C19H33NO2.HCl |
Formula Weight | 343.93g/mol |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
18792168
|
Tocris Bioscience™
6176/10 |
10 mg |
1525.00 NOK
10mg |
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18761508
|
Tocris Bioscience™
6176/50 |
50 mg |
5660.00 NOK
50mg |
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Description
S1P receptor agonist; undergoes phosphorylation by sphingosine kinase 2, which then binds S1P1,3,4 and 5 receptors (EC50 values are 0.3 - 0.6 nM for S1P1, 4 and 5 and ∽3 nM for S1P3). Immunosuppresant; sequesters lymphocytes in lymph nodes, reducing autoimmune response. Suppresses the development of EAE (an in vivo model of MS). Orally bioavailable and blood-brain barrier permeable.Specifications
Agonist | |
162359-56-0 | |
343.93g/mol | |
Store at -20°C |
Sphingosine-1-phosphate Receptor | |
C19H33NO2.HCl | |
Fingolimod, Gilenya | |
Sphingosine-1-phosphate Receptor Agonists |
For Research Use Only