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Tocris Bioscience™ FTY 720

Potent S1P receptor agonist; also immunosuppressant

1525.00 NOK - 5660.00 NOK

Specifications

Product Type Agonist
Target Proteins Sphingosine-1-phosphate Receptor
CAS 162359-56-0
Molecular Formula C19H33NO2.HCl
Formula Weight 343.93g/mol
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
18792168
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Tocris Bioscience™
6176/10
10 mg
1525.00 NOK
10mg
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18761508
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Tocris Bioscience™
6176/50
50 mg
5660.00 NOK
50mg
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Description

Description

S1P receptor agonist; undergoes phosphorylation by sphingosine kinase 2, which then binds S1P1,3,4 and 5 receptors (EC50 values are 0.3 - 0.6 nM for S1P1, 4 and 5 and ∽3 nM for S1P3). Immunosuppresant; sequesters lymphocytes in lymph nodes, reducing autoimmune response. Suppresses the development of EAE (an in vivo model of MS). Orally bioavailable and blood-brain barrier permeable.
Specifications

Specifications

Agonist
162359-56-0
343.93g/mol
Store at -20°C
Sphingosine-1-phosphate Receptor
C19H33NO2.HCl
Fingolimod, Gilenya
Sphingosine-1-phosphate Receptor Agonists
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