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Human FRAP1 (mTOR), GST Tag Recombinant Protein

Brand: Invitrogen PV4753

Product Code. 10012913

10400.00 NOK / Each

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Description

FRAP1 (mTOR) is a serine⁄threonine kinase that plays a critical role in cellular growth and proliferation. Perturbations in the mTOR⁄PI3-kinase⁄AKT pathway are associated with numerous forms of cancer. FRAP1 is also the target of rapamycin and its analogues, which are currently used as immunosuppressants and cancer therapeutics.

Specifications

Accession Number	NP_004949.1
Molecular Weight (g/mol)	163.9 kDa
Gene Alias	FRAP1 (mTOR)
Protein Length	aa 1360-2549
Recombinant	Recombinant
Content And Storage	Storage Buffer: 50 mM Tris, pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.1% Polysorbate 20, 2 mM DTT, 50% Glycerol Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.
Kinase Group	Ser⁄Thr Kinases: Atypical
System Compatibility	LanthaScreen™ Antibody, LanthaScreen™ Substrate, Z'-LYTE™
Target Gene	FK506 binding protein 12-rapamycin associated protein 1
Protein Family	Kinases & Inhibitors
Form	Liquid
Research Category	Signal Transduction, Drug Development, Oncology

For Use With (Application)	Kinase Assay
Quantity	10 μg
KinaseFamily	PIKK Kinase Family
Species	Human
Protein Tag	GST Tag
Assay Entry	Biochemical phospho-specific activity (no antibody), Biochemical terbium phospho-specific activity, Biochemical binding/kinetic
Shipping Condition	Dry Ice
Target Entry	mTOR, FRAP1
Expression System	Baculovirus
Protein Form	Recombinant, Catalytic
Protein Subtype	Serine/Threonine Kinases

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Human FRAP1 (mTOR), GST Tag Recombinant Protein

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