missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Estrone, 99+%, Thermo Scientific Chemicals
Estrone, 99%, CAS#53-16-7, is one of the major mammalian estrogen, is a steroid and a sex hormone. It is synthetized from cholesterol and secreted mainly from the gonads. It also presents antineoplastic and bone density conservative activities.
Brand: Thermo Scientific Acros 117840010
765.72 NOK valid until 2025-12-31
Use promo code "25339" to get your promotional price.
| Quantity | 1 g |
|---|---|
| Packaging | Glass bottle |
View more versions of this product
This item is not returnable.
View return policy
Description
This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
• Estrone is an aromatized C18 steroid considered one of the major mammalian estrogen and a sex hormone. It shows antineoplastic and bone density conservative activities.
• This compound can interact with estrogen receptors in target tissues to produce similar effects to estradiol. Hormone-bound estrogen receptors dimerize, translocate to the nucleus of cells and bind to estrogen response elements (ERE) of genes. Binding to ERE alters the transcription rate of affected genes.
Applications
• Estrone has the ability to increase the hepatic synthesis of sex hormone binding globulin (SHBG), thyroid-binding globulin (TBG), and other serum proteins.
• It can suppress the release of follicle-stimulating hormone and luteinizing hormone.
• This compound can be produced from androstenedione or testosterone via estradiol. In vivo, it can be generated mainly in the ovaries, placenta, and peripheral tissues (especially adipose tissue) through conversion of androstenedione. It may be metabolized to 16-α-hydroxyestrone, which may be reduced to estriol by estradiol dehydrogenase.
• It has been used as medium supplement for hormone-based degranulation studies of natural killer cells.
• It is used as medium component for monitoring fatty acid synthase activity in breast adenocarcinoma cell lines.
Chemical Identifiers
| 53-16-7 | |
| 270.36 | |
| estrone, folliculin, oestrone, theelin, estrovarin, estrugenone, follicular hormone, kestrone, estron, follicunodisShow More | |
| CHEBI:17263 | |
| CC12CCC3C(C1CCC2=O)CCC4=C3C=CC(=C4)O |
| C18H22O2 | |
| DNXHEGUUPJUMQT-CBZIJGRNSA-N | |
| 5870 | |
| (8R,9S,13S,14S)-3-hydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-oneShow More |
Specifications
| 53-16-7 | |
| White | |
| Authentic | |
| Glass bottle | |
| 1 g | |
| + 158.00 (20.00°C c=1,dioxane) | |
| estrone, folliculin, oestrone, theelin, estrovarin, estrugenone, follicular hormone, kestrone, estron, follicunodis | |
| DNXHEGUUPJUMQT-CBZIJGRNSA-N | |
| (8R,9S,13S,14S)-3-hydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one | |
| 5870 | |
| 270.36 | |
| 99+% | |
| Estrone |
| 258.0°C to 261.0°C | |
| 0.5% max. (105°C, 3 hrs) | |
| 99% min. (on dried substance) (HPLC) | |
| C18H22O2 | |
| 15,3763 | |
| + 158.00 | |
| Solubility in water: 0.03g/L. | |
| CC12CCC3C(C1CCC2=O)CCC4=C3C=CC(=C4)O | |
| 270.36 | |
| CHEBI:17263 | |
| passes test | |
| Crystalline Powder or Crystals |
Safety and Handling
Product Identifier
Signal Word
Hazard Category
Hazard Statement
Precautionary Statement
- Estrone
Signal Word
- Danger
Hazard Category
- Carcinogenicity Category 2
- Reproductive toxicity on or via lactation
- Reproductive toxicity Category 1A
Hazard Statement
- H351-Suspected of causing cancer.
- H360FD-May damage fertility. May damage the unborn child.
- H362-May cause harm to breast-fed children.
Precautionary Statement
- P201-Obtain special instructions before use.
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P308+P313-IF exposed or concerned: Get medical advice/attention.
Certificates
A lot number is required to show results for certificates. To find your lot number on previous orders use our order status area.
5 results found
| Lot Number | Certificate Type | Date | Catalog Number |
|---|---|---|---|
| A0394070 | Certificate of Analysis | 15/12/2022 | 117840050,117840250,117840010 |
| A0445851 | Certificate of Analysis | 16/09/2022 | 117840050,117840250,117840010 |
| A0439929 | Certificate of Analysis | 15/03/2022 | 117840050,117840250,117840010 |
| A0437173 | Certificate of Analysis | 10/12/2021 | 117840050,117840250,117840010 |
| A0431326 | Certificate of Analysis | 23/06/2021 | 117840050,117840250,117840010 |
Product Content Correction
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
Product Title
Estrone, 99+%, Thermo Scientific Chemicals > 1g; Glass bottle
Spot an opportunity for improvement?Share a Content Correction