Learn More
Thermo Scientific™ DSS (disuccinimidyl suberate), No-Weigh™ Format
Crosslink amines to amines with disuccinimidyl suberate composed of NHS-ester groups with a membrane-permeable, mid-length spacer for intracellular protein crosslinking.
Brand: Thermo Scientific™ A39267
Description
Thermo Scientific™ Pierce DSS, also called disuccinimidyl suberate, is noncleavable and membrane permeable crosslinker that contains an amine-reactive N-hydroxysuccinimide (NHS) ester at each end of an 8-carbon spacer arm.
- Reactive groups: NHS ester (both ends)
- Reactive towards: amino groups (primary amines)
- Amine reactive sulfo-NHS ester reacts rapidly with any primary amine-containing molecule
- Membrane-permeable, allowing for intracellular crosslinking
- High purity, crystalline reagent can be used to create high-purity conjugates
- Non-cleavable
- Water-insoluble (dissolve first in DMF or DMSO); compare to BS3 (Sulfo-DSS)

Specifications
Amine-Amine | |
DSS | |
No | |
Upon receipt store desiccated at 4°C. | |
Ambient | |
Chemical Labeling | |
NHS Ester | |
Solid | |
DMF, DMSO | |
No |
No | |
368.35 | |
11.4 Å | |
Yes | |
No-Weigh™ | |
Homobifunctional | |
Medium (10 to 30 Å) | |
10 x 2 mg | |
Standard, Single-use | |
Crosslinker |
Certificates
A lot number is required to show results for certificates. To find your lot number on previous orders use our order status area.
Lot Number | Certificate Type | Date | Catalog Number |
---|---|---|---|
ZL402938 | Certificate of Analysis | 12/02/2025 | A39267 |
ZJ402223 | Certificate of Analysis | 12/02/2025 | A39267 |
ZJ402223 | Certificate of Analysis | 16/12/2024 | A39267 |
ZJ399922 | Certificate of Analysis | 19/10/2024 | A39267 |
ZG394799 | Certificate of Analysis | 08/08/2024 | A39267 |
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
For Research Use Only. Not for use in diagnostic procedures.