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DNA-PK Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA123197
2960.14 NOK valid until 2025-03-21
Use promo code "24111" to get your promotional price.
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Description
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
DNA-PK is a heterotrimeric, DNA-dependent protein kinase that initiates signaling cascades in response to DNA damage. DNA-PK is an atypical kinase, closely related to the PI3 kinases, and is often potently inhibited by small molecules designed to target PI3 kinases. DNA-PK encodes a component of the mediator complex, a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, possibly by interacting with RNA polymerase II and promoting the formation of a transcriptional pre-initiation complex. Multiple transcript variants encoding different isoforms have been found for DNA-PK.
Specifications
| DNA-PK | |
| Polyclonal | |
| Unconjugated | |
| PRKDC | |
| AI326420; AU019811; DNA-dependent protein kinase catalytic subunit; DNAPDcs; DNAPK; DNA-PK catalytic subunit; DNA-PKcs; DNPK1; DOXNPH; doxorubicin nephropathy; dxnph; hyper-radiosensitivity of murine scid mutation, complementing 1; HYRC; HYRC1; I79_017613; IMD26; p350; p460; Prkdc; protein kinase, DNA activated, catalytic polypeptide; protein kinase, DNA-activated, catalytic polypeptide; scid; severe combined immunodeficiency; slip; Xrcc7 | |
| Rabbit | |
| 50 μL | |
| Primary | |
| Hamster, Human, Mouse, Rat | |
| Antibody | |
| IgG |
| Gel Shift, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot | |
| Conc. Not Determined | |
| whole serum with 0.09% sodium azide | |
| P78527, P97313 | |
| PRKDC | |
| Full length human DNA PKcs | |
| RUO | |
| 100770748, 19090, 360748, 5591 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
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Product Title
DNA-PK Polyclonal Antibody, Invitrogen™ > 50 μL; Unconjugated
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