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Desmoplakin Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA589145
This item is not returnable.
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Description
Positive Samples: HepG2; Cellular Location: Cell junction, Cytoplasm, cytoskeleton, desmosome Immunogen sequence: FSDTLEESSP IAAIFDTENL EKISITEGIE RGIVDSITGQ RLLEAQACTG GIIHPTTGQK LSLQDAVSQG VIDQDMATRL KPAQKAFIGF EGVKGKKKMS AAEAVKEKWL PYEAGQRFLE FQYLTGGLVD PEVHGRISTE EAIRKGFIDG RAAQRLQDTS SYAKILTCPK TKLKISYKDA INRSMVEDIT GLRLLEAASV SSKGLPSPYN MSSAPGSRSG SR
Desmoplakin (DSP) is a major high molecular weight protein of the desmosomes. It is involved in the organization of the desmosomal cadherin-plakoglobin complexes into discrete plasma membrane domains and in the anchoring of intermediate filaments to the desmosomes. Desmoplakin mutations are associated with Keratoderma and cardiomyopathy.
Specifications
| Desmoplakin | |
| Polyclonal | |
| Unconjugated | |
| DSP | |
| 2300002E22Rik, 250/210 kDa paraneoplastic pemphigus antigen, 5730453H04Rik, AA407887, AA407888, AW109828, DCWHKTA, dermatan sulfate proteoglycan 3, desmoplakin, desmoplakin I/II, Desmoplakin II, desmoplakin, LOW QUALITY PROTEIN: desmoplakin, Desmoplakin-I, desmosomal cytoskeletal connector molecule, DP, Dsp, dspg3, Oculoglycan, Opt, Optc, optcl, Opticin, rul, SLRP, SLRP protein, small leucine-rich repeat protein, small leucine-rich repeat protein (SLRP), wu:fb81a05, zgc:101047 | |
| Rabbit | |
| Affinity Chromatography | |
| RUO | |
| 109620, 1832, 306871 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot | |
| 3.60 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide, pH 7.3 | |
| E9Q557, P15924 | |
| DSP | |
| A synthetic peptide corresponding to a sequence within amino acids 2609-2830 of human Desmoplakin (NP_0044062) | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |