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Deoxynivalenol, Tocris Bioscience™

Product Code. 18732744
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Quantity:
1 mg
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Description

Mycotoxin; potent protein synthesis inhibitor

Tricothecene mycotoxin and potent protein synthesis inhibitor. Exhibits cytotoxic activity in vivo via the ribotoxic stress response. Induces p38-mediated gene expression and apoptosis in leukocytes; activity results in systemic expression of interleukin-6 (IL-6) and other proinflammatory cytokines. Also induces migration of NF-κB into the nucleus.

Specifications

CAS 51481-10-8
Molecular Formula C15H20O6
MDL Number MFCD09039270
Quantity 1 mg
Synonym deoxynivalenol, vomitoxin, dehydronivalenol, 4-deoxynivalenol, 4-desoxynivalenol, desoxynivalenol, unii-jt37hyp23v, ccris 7801, rd toxin, jt37hyp23v
InChI Key LINOMUASTDIRTM-QGRHZQQGSA-N
SMILES CC1=C[C@H]2O[C@@H]3[C@H](O)C[C@@](C)([C@]33CO3)[C@@]2(CO)[C@H](O)C1=O
IUPAC Name (1'R,2S,2'R,3'S,7'R,9'R,10'R)-3',10'-dihydroxy-2'-(hydroxymethyl)-1',5'-dimethyl-8'-oxaspiro[oxirane-2,12'-tricyclo[7.2.1.0²,⁷]dodecan]-5'-en-4'-one
Molecular Weight (g/mol) 296.32
PubChem CID 40024
Formula Weight 296.32
Percent Purity 98%
Chemical Name or Material Deoxynivalenol
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