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Deguelin, MedChemExpress
MedChemExpress Deguelin, a naturally occurring rotenoid, acts as a chemopreventive agent by blocking multiple pathways like PI3K-Akt, IKK-NF-κB, and MAPK-mTOR-survivin-mediated apoptosis. Deguelin binding to Hsp90 leads to a decreased expression of numerous oncogenic proteins, including MEK1/2, Akt, HIF1α, COX-2, and NF-κB.
Brand: Medchem Express HY-13425
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Description
Deguelin, a naturally occurring rotenoid, acts as a chemopreventive agent by blocking multiple pathways like PI3K-Akt, IKK-NF-κB, and MAPK-mTOR-survivin-mediated apoptosis. Deguelin binding to Hsp90 leads to a decreased expression of numerous oncogenic proteins, including MEK1/2, Akt, HIF1α, COX-2, and NF-κB.Specifications
| Deguelin | |
| Light Yellow | |
| C23H22O6 | |
| (-)-Deguelin (-)-cis-Deguelin | |
| O=C1[C@]2([H])[C@](COC3=CC(OC)=C(OC)C=C32)([H])OC4=C5C=CC(C)(C)OC5=CC=C14 | |
| 394.42 | |
| Research | |
| Cancer-Kinase/protease |
| 522-17-8 | |
| Research | |
| 5 mg | |
| DMSO : 100 mg/mL (253.54 mM; Need ultrasonic) | |
| 394.42 | |
| 98.0% | |
| Solid |
Research purposes only