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DCA, Tocris Bioscience™
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Quantity:
100 mg
Description
Inhibitor of mitochondrial pyruvate dehydrogenase kinase (PDK). Shifts pyruvate metabolism from glycolysis and lactate production to glucose oxidation in the mitochondria. Induces mitochondrial-dependent apoptosis and reverses the inhibition/downregulation of KV1.5 channels in cancer but not normal cells. Decreases tumor growth in vitro and in vivo.
Specifications
Specifications
CAS | 2156-56-1 |
Quantity | 100 mg |
Molecular Formula | C2HCl2NaO2 |
MDL Number | MFCD00070489 |
Synonym | sodium dichloroacetate, sodium 2,2-dichloroacetate, dichloroacetic acid sodium salt, acetic acid, dichloro-, sodium salt, ceresine, dichloroacetate sodium, dichloroctan sodny czech, sodium dichloroacetate usan, ccris 7697, dichloroacetic acid, sodium salt |
InChI Key | LUPNKHXLFSSUGS-UHFFFAOYSA-M |
SMILES | [Na+].[O-]C(=O)C(Cl)Cl |
IUPAC Name | sodium 2,2-dichloroacetate |
Molecular Weight (g/mol) | 150.92 |
PubChem CID | 517326 |
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