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Cyclophosphamide, Tocris Bioscience™
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Quantity:
50 mg
Description
Nitrogen mustard alkylating agent and prodrug. Phosphoramide mustard (active metabolite) forms DNA cross-links leading to cell death. Inhibits aldehyde dehydrogenase 1 (ALDH1) through its degradation product acrolein. Chemotherapeutic for the treatment of breast cancer; regulates Bax and Bcl-2 expression when administered with etoposide (Cat. No. 1226) in breast cancer cell lines.
Specifications
Specifications
CAS | 50-18-0 |
Molecular Formula | C7H15Cl2N2O2P |
Quantity | 50 mg |
Synonym | cyclophosphamide, cyclophosphamid, cyclophosphane, cytophosphan, procytox, clafen, cytoxan, endoxan, neosar, cyclophosphamidum |
InChI Key | CMSMOCZEIVJLDB-UHFFFAOYSA-N |
SMILES | C1CNP(=O)(OC1)N(CCCl)CCCl |
IUPAC Name | N,N-bis(2-chloroethyl)-2-oxo-1,3,2$l^{5}-oxazaphosphinan-2-amine |
Molecular Weight (g/mol) | 261.083 |
PubChem CID | 2907 |
ChEBI | CHEBI:4027 |
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