missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Claudin 18 Mouse anti-Human, Mouse, Clone: 5G7F2, Proteintech
Mouse Monoclonal Antibody
Brand: Proteintech 66167-1-IG-150UL
This item is not returnable.
View return policy
Description
Claudin-18 is a tight junction protein expressed as lung-and stomach-specific isoforms which are generated by alternative splicing of the claudin-18 gene. The lung-specific form is a downstream target gene regulated by the T/EBP/NKX2.1 transcription factor. A splice variant lacking the C-terminal cytoplasmic domain also exists in mouse, but has not been confirmed in human. Human claudin-18 demonstrates 88% amino acid sequence identity to the mouse protein. Immunohistochemical studies have demonstrated complete membrane localization of claudin-18 in lung and stomach epithelial cells, while electron microscopy has shown that it is concentrated in the cell-cell borders of these cells. These features suggest a potentially important role for claudin-18 in the structure and function of tight junctions in the lung and stomach. Claudin-18 expression has also been reported in the inner ear.Specifications
| Claudin 18 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| P56856, P56857 | |
| CLDN18 | |
| Claudin 18 Fusion Protein Ag15517 | |
| 150 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG2a |
| Immunohistochemistry (Paraffin), Immunoprecipitation | |
| 5G7F2 | |
| Unconjugated | |
| CLDN18 | |
| claudin 18, CLDN18, SFTA5, SFTPJ | |
| Mouse | |
| Protein A | |
| RUO | |
| 51208, 56492 | |
| -20°C | |
| Liquid |
Product Content Correction
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?Share a Content Correction