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CISD2 Mouse anti-Human, Mouse, Rat, Zebrafish, Clone: 3D7A3, Proteintech
Mouse Monoclonal Antibody
1696.32 NOK - 4796.50 NOK
Specifications
Antigen | CISD2 |
---|---|
Clone | 3D7A3 |
Concentration | 1.65 mg/mL |
Applications | Western Blot, Immunohistochemistry (Paraffin), Immunocytochemistry, Immunofluorescence |
Classification | Monoclonal |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
16857635
|
Proteintech
66082-1-IG-20UL |
20 μL |
1696.32 NOK
20µL |
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16847635
|
Proteintech
66082-1-IG-150UL |
150 μL |
4796.50 NOK
150µL |
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Description
This monoclonal antibody is specific to CISD2 and does not cross-react with CISD1.
Defects in the CISD2 (CDGSH iron sulfur domain 2) gene are a cause of the neurodegenerative disorder Wolfram syndrome 2. CISD2 is a zinc finger protein that localizes to the endoplasmic reticulum and mitochondria and binds an iron/sulfur cluster. CISD2 interacts with Bcl-2 and can be displaced by the BH3-only protein BIK and contributes to the regulation of BIK-initiated autophagy. CISD2 deficiency in mice causes mitochondrial breakdown accompanied by autophagic cell death as well as the development of premature aging phenotype.Specifications
CISD2 | |
1.65 mg/mL | |
Monoclonal | |
Liquid | |
RUO | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
CDGSH iron sulfur domain 2, CDGSH2, CISD2, CISD2-Specific, ERIS, Miner1, MitoNEET related 1 protein, NAF 1, WFS2, ZCD2 | |
cisd2 | |
Primary | |
-20°C | |
CISD2 |
3D7A3 | |
Western Blot, Immunohistochemistry (Paraffin), Immunocytochemistry, Immunofluorescence | |
Unconjugated | |
Mouse | |
Human, Mouse, Zebrafish, Rat | |
Q7T326, Q8N5K1, Q9CQB5 | |
295457, 393354, 493856, 67006 | |
IgG2b | |
Protein A | |
Antibody |
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