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  6. CD49f (Integrin α6) Rat, anti-Mouse, PE, Clone: GoH3, STEMCELL Technologies

CD49f (Integrin α6) Rat, anti-Mouse, PE, Clone: GoH3, STEMCELL Technologies

Rat Monoclonal Antibody

Encompass_Preferred

3571.72 NOK - 5571.88 NOK

Specifications

Antigen CD49f (Integrin α6)
Clone GoH3
Applications Immunohistochemistry, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Functional Assay
Classification Monoclonal
Conjugate PE
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Products 2
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Product Code Brand Quantity Price Quantity & Availability  
17138701
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Stemcell Technologies
60037PE.1 		25 Tests
3571.72 NOK
25 tests
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17128701
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Stemcell Technologies
60037PE 		100 Tests
5571.88 NOK
100 tests
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Description

Description

  • The GoH3 antibody reacts with CD49f (integrin α6), an ∼150 kDa transmembrane glycoprotein that associates non-covalently with CD29 (integrin β1) or CD104 (integrin β4) to form the heterodimeric receptors VLA-6 and α6β4, which bind the extracellular matrix protein laminin
  • CD49f is a disulfide-linked dimer comprising an ∼120 kDa heavy chain and an ∼30 kDa membrane-bound light chain
  • Splice variants exist, which affect the cytoplasmic domain of the protein
  • CD49f is expressed on the surface of T cells, monocytes, platelets, placental trophoblasts, epithelial cells, and endothelial cells
  • It is involved in cell adhesion and regulating signaling pathways involved in a variety of processes, including the activation and proliferation of T cells, and the differentiation and maintenance of stem cell pluripotency
  • CD49f is considered the most important marker for selecting mouse mammary stem and progenitor cells
  • The GoH3 antibody reacts with an extracellular epitope on CD49f
Specifications

Specifications

CD49f (Integrin α6)
Immunohistochemistry, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Functional Assay
PE
Baboon, Cynomolgus, Pig, Human
Primary
GoH3
Monoclonal
Rat
IgG2a κ
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Product Certifications
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