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CD45RC Monoclonal Antibody (OX-22), FITC, Invitrogen™
Mouse Monoclonal Antibody
Brand: Invitrogen MA517461
This item is not returnable.
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Description
CD45RC (PTPRC) is a protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. It acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, the second affects the substrate specificity of the first. Upon T-cell activation, CD45RC recruits and dephosphorylates SKAP1 and FYN. Mutations of the gene can result in severe combined immunodeficiency and multiple sclerosis.
Specifications
| CD45RC | |
| Monoclonal | |
| 0.1 mg/mL | |
| PBS with 4-5mg/mL BSA and 0.02% sodium azide | |
| P04157 | |
| Ptprc | |
| Phytohaemagglutinin-activated rat lymph node cells | |
| 500 μg | |
| Primary | |
| Rat | |
| Antibody | |
| IgG1 |
| Flow Cytometry | |
| OX-22 | |
| FITC | |
| Ptprc | |
| B220; CD45; CD45 antigen; CD45 antigen isoform 1 precursor; CD45 antigen isoform 2 precursor; CD45 antigen isoform 3 precursor; CD45 antigen isoform 4 precursor; CD45 antigen isoform 5 precursor; CD45 antigen isoform 6 precursor; CD45R; GP180; LCA; L-CA; leucocyte common antigen; leukocyte common antigen; leukocyte common antigen A; leukocyte common antigen B; loc; LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase C; LY5; Ly-5; lymphocyte antigen 5; lymphocyte common antigen; Lyt-4; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; Protein tyrosine phosphatase, receptor-type, c polypeptide; protein tyrosine phosphatase; alternatively spliced; Ptprc; Receptor-type tyrosine-protein phosphatase C; RT7; T200; T200 glycoprotein; T200 leukocyte common antigen | |
| Mouse | |
| Protein G | |
| RUO | |
| 24699 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark. | |
| Liquid |