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CCL25/TECK Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 25285-1-AP-150UL
This item is not returnable.
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Description
Chemokines are likely to play an important role in regulating the trafficking of developing T cells within the thymus. Chemokine C-C thymus expressed chemokine (TECK), also designated chemokine ligand 25 (CCL25), small induc-ible cytokine A25, chemokine b-15 or CK b-15, is expressed predomitly in thymic dendritic cells, thymic epithelial cells and in the small intestine. TECK, a CCR9 ligand, has suppressive activity against immature subsets of myeloid progenitors which have been stimulated to proliferate by multiple growth factors. TECK delivers signals through CCR9, which is important for the nav-igation of developing thymocytes. Bone marrow pre-pro-B cells and cells capable of generating pro-B colonies in the presence of interleukin-7 and Flt-3 ligand migrate to TECK, a response lost in later stages of B cell development.Specifications
CCL25/TECK | |
Polyclonal | |
Unconjugated | |
CCL25 | |
C C motif chemokine 25, CCL25, Chemokine TECK, Ckb15, SCYA25, Small inducible cytokine A25, TECK, Thymus expressed chemokine | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
6370 | |
-20°C | |
Liquid |
Immunohistochemistry (Paraffin), Western Blot | |
0.29 mg/mL | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
O15444 | |
CCL25 | |
CCL25/TECK Fusion Protein Ag17994 | |
150 μL | |
Primary | |
Human | |
Antibody | |
IgG |