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Calmodulin 3 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA529980
This item is not returnable.
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Description
Recommended positive controls: Mouse brain. Predicted reactivity: Mouse (100%), Rat (100%), Pig (100%), Bovine (100%), Guinea pig (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Calcium binding proteins (CaBP) play a crucial role in the calcium-mediated cellular signal transduction pathway in the central nervous system. The CaBP family shares much similarity with CaM I (calmodulin), and it has been shown that CaBP proteins can substitute functionally for, and possibly augment the function of, CaM I. CaBP7 (Calcium-binding protein 7), contains two EF-hand domains for calcium binding and shares 70% homology with CaBP8 and 50% homology with CaM I. It negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity. CaBP7 and 8 possess a targeting mechanism that is unique amongst the CaBPs that may contribute to differential functional Ca2+-sensing by these family members.
Specifications
| Calmodulin 3 | |
| Polyclonal | |
| Unconjugated | |
| CALM3 | |
| Calm; CALM1; Calm2; Calm3; CALML2; calmodulin; calmodulin 1; Calmodulin 1 (phosphorylase kinase, delta); calmodulin 3; calmodulin 3 (phosphorylase kinase, delta); Calmodulin III; calmodulin-1; Calmodulin-2; Calmodulin-3; Cam; Cam1; CAM2; Cam3; CaMA; CAMB; Camc; CAMI; CaMII; CAMIII; CPVT4; DD132; epididymis secretory protein Li 72; HEL-S-72; LQT14; PHKD; PHKD3; phosphorylase kinase subunit delta; phosphorylase kinase, delta subunit; prepro-calmodulin 1; prepro-calmodulin 3; R75142; RNCAMIII | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 12315, 24244, 808 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Western Blot | |
| 0.48 mg/mL | |
| 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7 | |
| P0DP25, P0DP28, P0DP31 | |
| CALM3 | |
| Recombinant protein fragment corresponding to a region within amino acids 1 and 99 of Human Calmodulin 3 | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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