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Tocris Bioscience™ BAG 956

Dual PI 3-kinase and PDPK1 (PDK1) inhibitor

Brand: Tocris Bioscience™ 3606/10

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Product Code. 18025612

2485.00 NOK / 10mg

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Description

BAG 956 is a dual PDPK1 (PDK1) and class I PI 3-K inhibitor (IC50 values are 245, 56, 446, 35 and 117 nM for PDPK1 and PI 3-K p110 -α, -β, -δ, and -γ respectively). Inhibits cellular AKT phosphorylation at Thr308. Blocks cell proliferation, causing arrest in G1 phase of the cell cycle. Slows tumor progression in mouse xenograft models.

Specifications

Purity	98%
Quantity	10 mg
Molecular Weight (g/mol)	427.5

Content And Storage	Store at -20°C
Product Type	BAG 956
Inhibitors	BAG 956

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Tocris Bioscience™ BAG 956

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