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Azithromycin

Product Code. 18035262
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Quantity:
50 mg
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Description

Antibiotic; inhibits 50S ribosomal subunit formation and elongation at transpeptidation

Azithromycin is a macrolide antibiotic. Inhibits 50S ribosomal subunit formation and elongation at transpeptidation step in gram-positive and gram-negative organisms. Orally active with improved pharmacokinetics over erythromycin in mouse models. Inhibits autophagy. Predicted to disrupt binding of SARS-CoV-2 spike protein to ACE2.

Specifications

Type Azithromycin
CAS 83905-01-5
Molecular Formula C38H72N2O12
MDL Number MFCD00873574,MFCD01862248,MFCD03191387
Synonym 13-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-o
InChI Key MQTOSJVFKKJCRP-OHJWJPDZSA-N
SMILES CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)C(C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@](C)(O)C[C@@H](C)CN(C)[C@H](C)[C@@H](O)[C@]1(C)O
IUPAC Name (2R,3S,4R,5R,8R,10R,11R,13S,14R)-11-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-2-ethyl-3,4,10-trihydroxy-13-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-3,5,6,8,10,12,14-heptamethyl-1-oxa-6-azacyclopentadecan-15-one
Molecular Weight (g/mol) 749.00
PubChem CID 133109198
Formula Weight 748.98
Percent Purity 99%
Quantity 50 mg
Chemical Name or Material Azithromycin
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