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Acrosomal Vesicle Protein Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA596930
This item is not returnable.
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Description
Immunogen sequence: QPNELSGSID HQTSVQQLPG EFFSLENPSD AEALYETSSG LNTLSEHGSS EHGSSKHTVA EHTSGEHAES EHASGEPAAT EHAEGEHTVG EQPSGEQPSG EHLSGEQPLS ELESGEQPSD EQPSGEHGSG EQPSGEQASG EQPSGEHASG EQASGAPISS TSTGTILNCY TCAYMNDQGK CLRGEGTCIT QNSQQCMLKK IFEGGKLQFM VQGCENMCPS MNLFSHGTRM QIICCRNQSF CNKI; Positive Samples: Mouse pancreas; Cellular Location: Cytoplasmic vesicle, acrosome, secretory vesicle
This gene encodes a testis-specific, differentiation antigen, acrosomal vesicle protein 1, that arises within the acrosomal vesicle during spermatogenesis, and is associated with the acrosomal membranes and matrix of mature sperm. This gene consists of 4 exons and its alternative splicing generates multiple distinct transcripts, which encode protein isoforms ranging from 81 to 265 amino acids. The longest transcript is the most abundant, comprising 53-72% of the total acrosomal vesicle protein 1 messages; the second largest transcript comprises 15-32%; the third and the fourth largest transcripts account for 3.4-8.3% and 8.7-12.5%, respectively; and the remaining transcripts combined account for < 1% of the total acrosomal vesicle protein 1 message. It is suggested that phenomena of cryptic splicing and exon skipping occur within this gene. The acrosomal vesicle protein 1 may be involved in sperm-zona binding or penetration, and it is a potential contraceptive vaccine immunogen for humans.![TRUSTED_SUSTAINABILITY](/content/dam/fishersci/glyphs/Sustain_Badge.png)
Specifications
Acrosomal Vesicle Protein | |
Polyclonal | |
Unconjugated | |
ACRV1 | |
acrosomal protein SP-10, Acrosomal vesicle protein 1, Acrv1, D11S4365, Msa63, MSA-63, rSP10, Sp10, SP-10, SPACA2, sperm membrane protein, sperm protein 10 | |
Rabbit | |
Affinity Chromatography | |
RUO | |
60353 | |
-20° C, Avoid Freeze/Thaw Cycles | |
Liquid |
Western Blot | |
0.22 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3 | |
P26436, P50289 | |
ACRV1 | |
Recombinant fusion protein containing a sequence corresponding to amino acids 22-265 of human ACRV1 (NP_0016031) | |
100 μL | |
Primary | |
Rat | |
Antibody | |
IgG |