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  6. 4-Nitrophenyl chloroformate, 97%, Thermo Scientific Chemicals

4-Nitrophenyl chloroformate, 97%, Thermo Scientific Chemicals

Product Code. 11385229
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Quantity:
5 g
25 g
100 g
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Description

4-Nitrophenyl chloroformate is used in the synthesis of poly(oxyethylene) modified dextrans. It is also used to prepare a cleavable, heterobifunctional cross-linker for reversible conjugation of amines to thiol-modified DNA. Further, it is used in the synthesis of mixed, activated carbonates, thiocarbonates and activated urethanes. In addition to this, it is used in the preparation of 4-nitrophenyl diazoacetate with diazomethane.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
4-Nitrophenyl chloroformate is used in the synthesis of poly(oxyethylene) modified dextrans. It is also used to prepare a cleavable, heterobifunctional cross-linker for reversible conjugation of amines to thiol-modified DNA. Further, it is used in the synthesis of mixed, activated carbonates, thiocarbonates and activated urethanes. In addition to this, it is used in the preparation of 4-nitrophenyl diazoacetate with diazomethane.

Solubility
Soluble in acetone, chloroform, acetone, toluene and benzene.

Notes
Moisture sensitive. Store in a cool place. Incompatible with water, acids, alcohols, ammonia, amines and strong bases.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 7693-46-1
Molecular Formula C7H4ClNO4
Molecular Weight (g/mol) 201.562
MDL Number MFCD00007321
InChI Key NXLNNXIXOYSCMB-UHFFFAOYSA-N
Synonym 4-nitrophenyl chloroformate, carbonochloridic acid, 4-nitrophenyl ester, chloroformic acid 4-nitrophenyl ester, p-nitrophenyl chloroformate, chloroformic acid p-nitrophenyl ester, 4-nitrophenyl carbonochloridate, formic acid, chloro-, p-nitrophenyl ester, 4-nitrophenylchlorocarbonat, 4-nitrophenyl choroformate
PubChem CID 82129
IUPAC Name (4-nitrophenyl) carbonochloridate
SMILES C1=CC(=CC=C1[N+](=O)[O-])OC(=O)Cl

Specifications

Melting Point 75°C to 82°C
Boiling Point 159°C to 162°C (19 mmHg)
Flash Point >110°C (230°F)
Odor Acrid
Quantity 5 g
UN Number UN3261
Beilstein 518127
Sensitivity Moisture sensitive
Solubility Information Soluble in acetone,chloroform,acetone,toluene and benzene.
Formula Weight 201.57
Percent Purity 97%
Chemical Name or Material 4-Nitrophenyl chloroformate
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RUO – Research Use Only

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