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  6. Thermo Scientific Chemicals 3'-Azido-3'-deoxythymidine, 98%

Thermo Scientific Chemicals 3'-Azido-3'-deoxythymidine, 98%

Product Code. 15496739
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Quantity:
1 g
5 g
25 g
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This item is not returnable. View return policy

Description

Anti-viral agent

3'-Azido-3'-deoxythymidine is a Anti-viral agent, and also used as a reverse transcriptase inhibitor active against HIV-1 virus that blocks the incorporation of nucleotides into growing DNA strands. Useful for antiviral and anticancer studies. 3?-Azido-3?-deoxythymidine enters CNS by diffusion and causes irreversible telomere shortening.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
3′-Azido-3′-deoxythymidine is a Anti-viral agent, and also used as a reverse transcriptase inhibitor active against HIV-1 virus that blocks the incorporation of nucleotides into growing DNA strands. Useful for antiviral and anticancer studies. 3′-Azido-3′-deoxythymidine enters CNS by diffusion and causes irreversible telomere shortening.

Solubility
Soluble in water.

Notes
Light Sensitive & Hygroscopic. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 30516-87-1
Molecular Formula C10H13N5O4
Molecular Weight (g/mol) 267.25
MDL Number MFCD00006536
InChI Key HBOMLICNUCNMMY-CFQLRCIDNA-N
Synonym azt; azidothymidine; zdv; zidovudine, 1-2r-4-azido-5-hydroxymethyl oxolan-2-yl-5-methyl-3h-pyrimidine-2,4-dione
PubChem CID 455007
SMILES CC1=CN([C@H]2C[C@H](N=[N+]=[N-])[C@@H](CO)O2)C(=O)NC1=O

Specifications

Melting Point 113°C to 115°C
Color White
Quantity 1 g
Beilstein 3595791
Sensitivity Light sensitive; Very Hygroscopic
Merck Index 1410123
Solubility Information Soluble in water.
IUPAC Name 1-[(2R,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
Formula Weight 267.24
Percent Purity 98%
Physical Form Powder
Chemical Name or Material 3'-Azido-3'-deoxythymidine
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Safety and Handling

compliance-icons
Signal Word
  • Warning
 Hazard Category
  • Carcinogenicity Category 2
 Hazard Statement
  • H351-Suspected of causing cancer.
 Precautionary Statement
  • P201-Obtain special instructions before use.
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P308+P313-IF exposed or concerned: Get medical advice/attention.

RUO – Research Use Only

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