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Thermo Scientific™ 2'-Fluoro-iBu-G Phosphoramidite, standard grade, 28-400 finish bottle

2'-Fluoro-iBu-G CEP is a phosphoramidite containing 5' DMT and the nucleoside guanosine (G) with 2'-Fluoro protection, for use in oligonucleotide synthesis.

Brand:  Thermo Scientific™ 27-1607-12

254.34 NOK valid until 2024-12-31
Use promo code "21651" to get your promotional price.

Product Code. 17927192

  • 490.10 NOK / 500mg

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Description

Description

2'-Fluoro-iBu-G CEP is a phosphoramidite containing 5' DMT and the nucleoside guanosine (G) with 2'-Fluoro protection, for use in oligonucleotide synthesis. Located in the ideal oligo position, the highly electronegative fluorine (2'-Fluoro) modification adopts a more thermodynamically stable A-form helix on hybridization to its target. Showing improved affinity and some nuclease resistance (compared to 2'-OH), the 2'-F modification has been proven useful in antisense, siRNA, and aptamer applications. The 'standard grade' marking denotes a baseline level of purity verified with analytical methods, and proven to be suitable for most oligo synthesis requirements. This product is supplied in a 30-mL amber bottle with a 28-400 finish neck style, which is compatible with most MerMade synthesizers.

Features:
• Full chemical name: 5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyryl-2'-fluoroguanosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
• Molecular formula: C44H53FN7O8P
• Base: G
• Base Protection: iBu
• Formula weight: 857.4 g/mol
• CAS number: 144089-97-4
• HPLC purity: >98%
• 31P NMR purity: ≥98%

TRUSTED_SUSTAINABILITY
Specifications

Specifications

MerMade Synthesizers
Store in freezer (at or below -20°C).
2in-Fluoro modified
98%
Phosphoramidite
RNA
2in-Fluoro-iBu-G CEP
Guanosine (G)
Room Temperature
0.5 g
Standard
Powder
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