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Tocris Bioscience™ BIX 02189
Selective MEK5 and ERK5 inhibitor
Brand: Tocris Bioscience™ 4842/10
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Description
BIX 02189 is a selective MEK5 and ERK5 inhibitor (IC50 values are 1.5 and 59 nM respectively). Inhibits sorbitol-induced ERK5 phosphorylation in HeLa cells. Selective for MEK5 and ERK5 over MEK1/2, ERK1/2 and a panel of 87 kinases. Induces apoptosis in acute myeloid leukemia tumor cells.
Specifications
>98% | |
BIX 02189 | |
BIX 02189 |
10 mg | |
440.54 |
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Product Title
Tocris Bioscience™ BIX 02189 > 10mg
For Research Use Only
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