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  8. 1-Naphthyl PP1, Tocris Bioscience™

1-Naphthyl PP1, Tocris Bioscience™

Product Code. 18085502
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Quantity:
10 mg
50 mg
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Description

Src family kinase inhibitor; also inhibits c-Abl

Selective inhibitor of src family kinases v-Src and c-Fyn as well as the tyrosine kinase c-Abl. (IC50 values are 1.0, 0.6, 0.6, 18 and 22 μM for v-Src, c-Fyn, c-Abl, CDK2 and CAMK II respectively). Preferentially inhibits mutant over wild-type kinases (IC50 values are 1.5 vs 1000 nM for I338G v-src and v-src respectively).

Chemical Identifiers

CAS 221243-82-9
Molecular Formula C19H19N5
Molecular Weight (g/mol) 317.40
MDL Number MFCD03425471
InChI Key XSHQBIXMLULFEV-UHFFFAOYSA-N
Synonym 1-naphthyl pp1, 1-na-pp1, pp1 analog, 1-tert-butyl-3-naphthalen-1-yl-1h-pyrazolo 3,4-d pyrimidin-4-amine, 4-amino-1-tert-butyl-3-1'-naphthyl pyrazolo 3,4-d pyrimidine, 1-1,1-dimethylethyl-3-1-naphthalenyl-1h-pyrazolo 3,4-d pyrimidin-4-amine, 1-na pp1, 1-tert-butyl-3-naphthalen-1-ylpyrazolo 3,4-d pyrimidin-4-amine
PubChem CID 4877
ChEBI CHEBI:52310
IUPAC Name 1-tert-butyl-3-(naphthalen-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
SMILES CC(C)(C)N1N=C(C2=C(N)N=CN=C12)C1=C2C=CC=CC2=CC=C1

Specifications

Quantity 10 mg
Formula Weight 317.39
Percent Purity >99%
Chemical Name or Material 1-Naphthyl PP1
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