Test
CaM kinase II inhibitor; water soluble version of KN 93 (Cat. No. 1278).
Used as cell-permeable, irreversible inhibitor of caspase activity. R&D Systems Pan Caspase Inhibitor Z-VAD-FMK binds to the active site of activated proteases irreversibly and inhibits apoptosis.
Potent ROCK inhibitor
Potent and selective negative allosteric modulator at mGlu1; also mGlu1 inverse agonist
MEK inhibitor
Antimicrobial peptide derivative of human cathelicidin
Potassium channel modulator; exerts subtype-specific effects
Potent and selective Lck and Src inhibitor; also inhibits SIK
Glucokinase activator
Stabilizes G-quadruplexes; induces DNA damage and cell cycle arrest
Potent VEGFR inhibitor; also inhibits other RTKs
Potent and selective polynucleotide kinase/phosphatase (PNKP) inhibitor
S1P2 receptor antagonist
Highly potent and selective 5-HT uptake inhibitor
Potent, dual orexin receptor antagonist