Test
Inhibits NF-κB activation
CaM kinase II inhibitor; water soluble version of KN 93 (Cat. No. 1278).
Used as cell-permeable, irreversible inhibitor of caspase activity. R&D Systems Pan Caspase Inhibitor Z-VAD-FMK binds to the active site of activated proteases irreversibly and inhibits apoptosis.
Potent EGFR-kinase inhibitor
Necroptosis inhibitor
Selective MEK5 and ERK5 inhibitor
Cdc42 inhibitor
Potent and selective TAK1 MAPKKK inhibitor
Potent and selective PLD1 inhibitor
Pan Jumonji inhibitor; active in vivo
Irreversible protein disulfide isomerase (PDI) inhibitor
Selective KDM2/7 inhibitor
High affinity and selective Smoothened (Smo) receptor antagonist
Potent and selective DGAT-1 inhibitor
YAP inhibitor