CAS RN 1421448-26-1
CAS RN 1421448-26-1
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Tocris Bioscience™ GN 44028
Potent HIF-1α inhibitor
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Medchem Express GN44028, MedChemExpress
MedChemExpress GN44028 is a potent and orally active hypoxia inducible factor (HIF)-1α inhibitor, with an IC50 of 14 nM. GN44028 inhibits hypoxia-induced HIF-1α transcriptional activity without suppressing HIF-1α mRNA expression, HIF-1α protein accumulation, or HIF-1α/HIF-1β heterodimerization. GN44028 can be used in the research of cancers.
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