Main Benefits
Optimize Aggregate Analysis of AAV-Based Gene Therapies with SurePac
Efficient
Baseline resolution of AAV monomers and aggregates in less than 4 minutes.
Adaptable
Preserved resolution even for injection of large volumes.
Reproducible
Consistent separation of AAVs across column lots.
Additional Information
Application Note
AAV-Based Gene Therapies
In the field of adeno-associated virus (AAV) analysis, understanding the critical attribute of aggregation is of utmost importance for therapeutic safety and efficacy. View our application note on size-exclusion chromatography of adeno-associated viruses with the SurePac™.
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Choosing the Right Sample Vial for Analysis of AAVs to Prevent Sample Loss
Analysis of viral capsids remains very challenging for numerous reasons. In particular, limited sample availability makes it difficult to maintain high sensitivity and repeatability. In this regard, using the correct sample vials for capsid analysis via liquid chromatography can constitute an important step in allowing for highly reproducible results.
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Why Should You Consider SEC to Analyze AAV Aggregates?
Understand why the critical attribute of aggregation is important for therapeutic safety and efficacy.
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Documentation
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Adeno-Associated Viruses (AAVs): Complete Workflow Solutions
Explore different solutions for AAV analysis, depending on your needs.
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BioPharma Workflow Solutions
Chromatography columns and consumables for key biopharma workflows.
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Adeno-Associated Viruses (AAVs): Complete Workflow Solutions
Analysis of viral capsids remains very challenging for numerous reasons.
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Size-exclusion Chromatography of Adeno-associated Viruses With the SurePac Bio 550 SEC MDi Column
In AAV production, separating the monomeric form from aggregates is critical for optimal gene therapy outcomes.
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